logo

Members


The Soberman Lab team - Boston, MA


Principal Investigator


Roy Soberman - Principal Investigator

Roy J. Soberman

I received my M.D. from New York University and house staff training at Bellevue Hospital in NY. My post-doctoral training in Biochemistry was at Harvard Medical School, and in Immunology at Brigham and Women’s Hospital. My original background is in the leukotrienes (bioactive lipids derived from arachidonic acid), enzymology, and inflammation. I am currently interested in how cells integrate the constantly changing array of extracellular signals to achieve an appropriate phenotype via the transient assembly of multiprotein complexes; particularly those held together by weak interactions. My overall management philosophy about labs is best expressed by management rule #3 of the late Kelly Johnson, the founding director of the Advanced Development Program at Lockheed, best known as the Skunk Works: “The number of people having any connection with the project must be restricted in an almost vicious manner. Use a small number of good people (10% to 25% compared to the so-called normal systems)”- In practical terms that translates into giving a relatively small group of outstanding investigators (6-8 max) the best possible equipment, facilities, and working environment.

soberman@helix.mgh.harvard.edu



Instructor


Carolyn Boudrea | The Soberman Lab

Angela (Bair) Schmider

After earning her Ph.D. in Pharmacology from the University of Illinois at Chicago, where she studied calcium signaling and vascular biology, Angie joined the Soberman Laboratory in 2008. She focuses on understanding the assembly and architecture of the leukotriene synthetic complex in myeloid cells by combining advanced imaging and biochemical techniques. She is supported by a K01 grant which was awarded in 2010.

aschmider@partners.org


Students


John Szeto | The Soberman Lab

John Szeto, graduate student

John graduated with a BS/MS in Pharmaceutical Sciences/Pharmacology from Northeastern University and is pursuing further graduate education at Harvard University. He has been a member of the lab since 2014. He is studying how 5-LO and FLAP organize on the nuclear membrane in response to different cytokines and how members of prostaglandin synthesis are organized in macrophages. 

jszeto@partners.org

Zoe Onion | The Soberman Lab

Zoe Onion, undergraduate student

Zoë is a junior at Harvard College and works as a summer student in the lab. She is working on how 5-LO and FLAP assemble on the nuclear membrane in response to different cytokines and how members of prostaglandin synthesis are organized in macrophages.

zonion@partners.org


Research Technician


Carolyn Boudrea | The Soberman Lab

Carolyn Boudreau

Carolyn received her B.S. in Biology from Tufts University and has worked in the Soberman lab since graduating in 2014. She studies the role of CD200R1 in neutrophil biology, as well as assisting with various other projects. She plans to pursue a Ph.D. in microbiology/virology.

cboudreau@partners.org

Matthew Godin | The Soberman Lab

Matt Godin

Matthew graduated from The University of Connecticut with a Bachelors degree in molecular and cellular biology in 2012. He is focused how the leukotriene biosynthetic complex reorganizes on the nuclear membrane in response to extracellular stimuli and on the role of G-protein signaling in ANCA vasculitis.

mgodin@partners.org


Alumni


Peter-Christmas-Soberman Research Laboratory Instructor

Peter Christmas

Peter received his Ph.D. from Liverpool University, U.K. He completed his post-doctoral fellowship in the Soberman laboratory and is now R01 funded. His interests are the biology of Cytochrome P450s, in particular CYP4F3, which controls the inactivation of LTB₄ in PMN and macrophages.


Rachel Vaivoda-Soberman Lab Research Technician

Rachel Vaivoda

Rachel received her BA from Bates College, and has worked in the Soberman group since graduating in 2011. She will be attending nursing school in the fall.


Christine-Vaine- Post Doctoral Fellow - Soberman Lab

Christine Vaine

Christine graduated from the University of Massachusetts, Amherst in 2005 with a B.S. in microbiology. She received her Ph.D. in immunology in 2010 from Dr. Robert Finberg’s laboratory at the University of Massachusetts Medical School in Worcester. Her graduate work focused on imaging antibody-mediated endocytosis pathways as well as characterizing particle-induced innate immune responses. She joined Dr. Soberman’s laboratory as a post-doctoral research fellow in 2010 to study the role of CD200R1 in mediating neutrophil biology.


Melissa Turman - Post doctoral fellow - Soberman Lab

Melissa Turman

Melissa received her Ph.D. in Chemistry from Vanderbilt University, where she studied structure-function relationships of cyclooxygenase metabolism and inhibition in the laboratory of Larry Marnett. She joined the Soberman laboratory in 2010. She studies how proteins in the leukotriene synthetic complex organize on the nuclear membrane.